Opportunity Information: Apply for CDC RFA GH21 2158

The CDC funding opportunity titled "Strengthening Urban Health Services and Models of Care in Kampala Capital City Authority (KCCA) - Uganda under PEPFAR" (Funding Opportunity Number CDC RFA GH21 2158) is a discretionary cooperative agreement designed to support Kampala's city health system in achieving and sustaining HIV and TB epidemic control while also improving readiness for other infectious and non-infectious threats that affect people living with HIV (PLHIV) and populations impacted by HIV and TB. The award is structured as a cooperative agreement, meaning the CDC expects to have substantial involvement with the recipient in planning, implementation, and monitoring of activities rather than acting only as a pass-through funder.

Funding is described in a somewhat unusual way: the Year 1 award ceiling is listed as 0 (none), while CDC anticipates approximately $2,000,000 in total funding for Year 1, contingent on the availability of funds. This typically signals that the agency is not setting a per-award cap in the normal way for that first budget period, but still expects to obligate funds around the stated estimate. The opportunity anticipated making one award. It falls under the health activity category and is associated with CFDA numbers 93.067 and 93.318. Eligibility is listed broadly as "Others," with further clarification expected in the full notice. The NOFO was posted March 3, 2021, with an original closing date of May 2, 2021 (applications due by 11:59 p.m. Eastern Time).

Programmatically, the NOFO focuses on four tightly linked strategies that aim to strengthen urban health governance, service delivery, and data systems in KCCA and its surrounding metropolitan area. The overall intent is to improve coordination across government and partners, reinforce the capacity of public health functions in a complex urban setting, and ensure HIV/TB services are resilient and integrated with broader disease prevention and response efforts.

Strategy 1 centers on partnerships and governance. The NOFO emphasizes collaboration to produce harmonized and integrated annual health work plans and monitoring and evaluation (M and E) plans, along with economic analyses that can guide resource allocation and decision-making. This strategy also highlights improved management and coordination of US government and other donor funds, and the strengthening of health information and laboratory systems. While HIV and TB are core priorities, the governance approach is meant to support a wider set of reportable infectious diseases and non-infectious conditions that affect PLHIV and communities impacted by HIV/TB, reflecting the reality that urban HIV outcomes are shaped by broader health system performance.

Strategy 2 focuses on ensuring HIV and TB service delivery by strengthening KCCA's capacity to perform essential public health functions needed for epidemic control. This includes building the operational ability to plan, coordinate, supervise, and continuously improve HIV and TB programs across the city and metropolitan area. A key feature is strengthening collaboration between the public and private sectors, recognizing that in an urban environment like Kampala a significant share of care is delivered through private clinics, pharmacies, and other non-government providers. The aim is to bring these providers into a more coordinated framework so standards, reporting, referral pathways, and quality improvement efforts work across the whole service network rather than in isolated pockets.

Strategy 3 emphasizes integration of HIV and TB work with other diseases and public health threats, with the explicit goal of protecting PLHIV and people affected by HIV/TB from epidemics and outbreaks. Activities include outbreak detection, investigation, and response capabilities, stronger laboratory systems, and surveillance for priority diseases. The strategy specifically calls out antimicrobial resistance (AMR) detection and control, which is increasingly important in settings with high infectious disease burdens and substantial antibiotic use. In practice, this strategy supports a more resilient system where HIV/TB platforms are not siloed but instead contribute to broader public health security and routine disease control, improving continuity of care during outbreaks and strengthening the city's ability to detect and respond rapidly to emerging threats.

Strategy 4 concentrates on health information systems integration for surveillance, monitoring and evaluation, and laboratory systems strengthening. The NOFO prioritizes supporting surveillance and laboratory monitoring systems for HIV and TB while also covering other disease priorities, with an emphasis on building epidemiologic capacity. This includes improving the ability to prevent, detect, and respond to disease threats through better analysis of routine data and the use of special surveys when needed. The intent is to move toward more complete, timely, and actionable data that can inform decision-making at facility, city, and partner levels, reduce fragmentation across parallel reporting systems, and improve accountability for results.

Taken together, the opportunity is aimed at improving how KCCA plans and governs health programs, how it delivers HIV/TB services across both public and private providers, how it integrates HIV/TB programming into broader outbreak preparedness and disease control (including AMR), and how it modernizes and connects surveillance, M and E, and laboratory information systems to support faster and better public health action in an urban setting.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Urban Health Services and Models of Care in Kampala Capital City Authority (KCCA)- Uganda under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067, 93.318.
  • This funding opportunity was created on Mar 03, 2021.
  • Applicants must submit their applications by May 02, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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