Opportunity Information: Apply for RFA HL 19 024

The Short-Term Research Education Program to Increase Diversity in Health-Related Research (R25 Clinical Trial Not Allowed), issued by the National Institutes of Health (NIH) within the Department of Health and Human Services and aligned with the National Heart, Lung, and Blood Institute (NHLBI), is a discretionary grant opportunity designed to build a stronger and more diverse biomedical, behavioral, and clinical research workforce. It uses the NIH Research Education Program (R25) mechanism, which is specifically meant to fund structured educational activities that prepare participants for research careers in NIH mission areas. In this case, the focus is on fields central to NHLBI, meaning topics connected to heart, lung, blood, and sleep-related research, along with the broader scientific and clinical disciplines that support those areas.

The central purpose of this funding announcement is to increase diversity in health-related research by supporting short-term research education experiences. Rather than funding a traditional research project, the program supports educational activities that help participants gain meaningful exposure to research environments, develop research-relevant skills, and strengthen their readiness to pursue further research training or careers. The funding announcement emphasizes “creative educational activities” with a primary focus on Research Experiences, which typically means hands-on, mentored experiences embedded in real research settings. The intent is to provide participants with practical opportunities to learn how research is done, how questions are formulated and tested, and how data and evidence are translated into biomedical knowledge and ultimately improvements in health.

A key boundary of this opportunity is captured in the label “Clinical Trial Not Allowed.” That means the proposed R25 program cannot include conducting an independent clinical trial as part of the grant’s supported activities. The program can still be connected to clinical and translational science broadly, but applicants must design their educational and research-experience components in a way that does not propose or rely on running a clinical trial under this award.

The opportunity is offered as a grant under a health-related funding activity category, and it is associated with multiple CFDA numbers (93.233, 93.837, 93.838, 93.839, 93.840), reflecting NHLBI’s broad portfolio and the fact that the program sits within established federal assistance listings tied to health research and research training infrastructure. The award information included in the source indicates an award ceiling of $119,000 and an expected total of 7 awards, which signals a relatively competitive, cohort-sized program intended to support a limited number of well-designed education efforts rather than a large number of small awards.

Eligibility is broad and includes many types of U.S.-based organizations that could plausibly host and administer research education programs. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (when not part of an institution of higher education); for-profit organizations other than small businesses; small businesses; and additional entities as clarified in the full funding announcement. This wide eligibility range reflects NIH’s interest in supporting strong education pipelines across different institutional contexts, including universities, research institutes, community-facing organizations, and other settings capable of delivering rigorous, mentored research experiences.

From an administrative standpoint, the funding opportunity is identified as RFA-HL-19-024. The source data lists a creation date of May 1, 2018, with an original closing date of May 6, 2021. In practical terms, those dates indicate when the opportunity was established and when it was last set to close under that announcement cycle, which matters for applicants tracking whether a particular RFA is still active or has been replaced by a newer announcement.

Overall, this program is best understood as a capacity-building and workforce-development effort. It is designed to expand participation in NHLBI-relevant research by supporting structured, hands-on research experiences and related educational elements that help individuals from diverse backgrounds enter and advance within biomedical, behavioral, and clinical research pathways. The emphasis is less on producing a single set of research findings and more on developing people, skills, mentorship relationships, and sustained interest and preparedness for research careers that ultimately strengthen the diversity and breadth of the health-related research workforce.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Short-Term Research Education Program to Increase Diversity in Health-Related Research (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.837, 93.838, 93.839, 93.840.
  • This funding opportunity was created on May 01, 2018.
  • Applicants must submit their applications by May 06, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $119,000.00 in funding.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)

What is the Short-Term Research Education Program to Increase Diversity in Health-Related Research (R25 Clinical Trial Not Allowed)?

This is a discretionary grant opportunity from the National Institutes of Health (NIH), within the Department of Health and Human Services, aligned with the National Heart, Lung, and Blood Institute (NHLBI). It uses the NIH Research Education Program (R25) mechanism to support structured educational activities that prepare participants for research careers in NIH mission areas, with a focus on NHLBI-relevant fields.

What is the primary goal of this funding opportunity?

The central purpose is to increase diversity in health-related research by supporting short-term research education experiences. The program is intended to strengthen the biomedical, behavioral, and clinical research workforce by helping participants gain meaningful exposure to research environments and develop research-relevant skills.

Which NIH institute is this program aligned with, and what topics are emphasized?

The program is aligned with the National Heart, Lung, and Blood Institute (NHLBI). It emphasizes fields central to NHLBI, including heart, lung, blood, and sleep-related research, as well as broader scientific and clinical disciplines that support those areas.

Is this grant meant to fund a traditional research project?

No. The R25 mechanism is intended to fund structured educational activities rather than a traditional research project. The emphasis is on research education and hands-on experiences that build skills and readiness for future research training or careers.

What kinds of activities are expected under this R25 program?

The funding announcement emphasizes "creative educational activities" with a primary focus on Research Experiences. This typically means hands-on, mentored experiences embedded in real research settings, where participants can learn how research questions are formulated, tested, and translated into biomedical knowledge and improvements in health.

What does "Clinical Trial Not Allowed" mean for applicants?

"Clinical Trial Not Allowed" means the proposed R25 program cannot include conducting an independent clinical trial as part of the grant-supported activities. Applicants can still design programs connected to clinical and translational science broadly, but they must avoid proposing or relying on running a clinical trial under this award.

Can the program still be related to clinical or translational science?

Yes. The program can be connected to clinical and translational science in a broad sense, but it must be designed so that the supported activities do not involve conducting an independent clinical trial under the R25 award.

What is the funding mechanism used for this opportunity?

The opportunity uses the NIH Research Education Program (R25) mechanism, which supports structured research education activities that prepare participants for research careers in NIH mission areas.

What is the funding opportunity announcement (FOA) or RFA number?

The funding opportunity is identified as RFA-HL-19-024.

What are the award ceiling and expected number of awards?

The source information indicates an award ceiling of $119,000 and an expected total of 7 awards. This suggests a competitive opportunity intended to support a limited number of well-designed research education efforts.

Which CFDA numbers are associated with this opportunity?

This opportunity is associated with multiple CFDA numbers: 93.233, 93.837, 93.838, 93.839, and 93.840. These reflect NHLBI's broad portfolio and its connection to established federal assistance listings tied to health research and research training infrastructure.

Who is eligible to apply?

Eligibility is broad and includes many U.S.-based organization types capable of hosting and administering research education programs. Eligible applicants include:

  • State, county, and local governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Federally recognized Native American tribal governments and other tribal organizations
  • Public housing authorities and Indian housing authorities
  • Nonprofit organizations with or without 501(c)(3) status (when not part of an institution of higher education)
  • For-profit organizations other than small businesses
  • Small businesses
  • Additional entities as clarified in the full funding announcement

Why is eligibility so broad for this program?

The wide eligibility range reflects NIH's interest in supporting strong research education pipelines across different institutional contexts, including universities, research institutes, community-facing organizations, and other settings that can deliver rigorous, mentored research experiences.

When was this opportunity created, and when did it close?

The source data lists a creation date of May 1, 2018, and an original closing date of May 6, 2021. These dates indicate when the opportunity was established and when it was last set to close under that announcement cycle.

What does the listed closing date imply for potential applicants today?

Based on the information provided, the original closing date was May 6, 2021. Applicants tracking this opportunity would need to confirm whether the announcement is still active or whether it has been replaced by a newer funding announcement.

What is this program ultimately trying to build or strengthen?

This program is best understood as a capacity-building and workforce-development effort. It aims to expand participation in NHLBI-relevant research by developing people, skills, mentorship relationships, and sustained preparedness for research careers, ultimately strengthening the diversity and breadth of the health-related research workforce.

Does the program focus more on producing research findings or developing researchers?

The emphasis is less on producing a single set of research findings and more on developing participants through structured, hands-on research experiences and related educational elements that support continued research training and career advancement.

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